Research School for Socio-Economic and
Natural Sciences of the Environment
Research School for Socio-Economic and
Natural Sciences of the Environment

Johanna Gutleben

Date: 21 November 2019
Time: 11:00 - 12:30
Location: Aula, building 362, Gen. Foulkesweg 1, Wageningen

Dissertation title: 

Ecological and biotechnical aspects of Aplysina-associated microorganisms

Group: Wageningen University, Microbiology
Promotor: Prof.dr. H. Smidt and R.H. Wijffels
Co-promotor: D. Sipkema

Extra information:


This thesis had the goal to increase our understanding of marine sponge microbial ecology by integrating both cultivation-dependent and –independent approaches. Chapter 1 introduced the sponge, the importance of these animals and summarized the current knowledge on functional aspects of sponge-associated microbiomes. In Chapter 2, six Aplysina species were screened for flavin-dependent tryptophan halogenase sequence variants as well as the composition and structure of their bacterial communities. . In Chapter 3, we investigated the global diversity and phylogenetic distribution of poribacteria among different sponge hosts. Chapter 4 describes several approaches to increase the cultivability of bacteria associated to the sponge Aplysina aerophoba. Chapter 5 reviewed ground-breaking studies that translated information derived from multi-omics into successful isolation strategies for previously unculturable microorganisms. Chapter 6 integrated the findings from the previous chapters and portrayed them in the light of recent work from within the field of sponge microbiology and ecology.

Dissertations with full text links

By September we will present an overview of SENSE dissertations on this page, with links to the full texts of the dissertations.