Research School for Socio-Economic and
Natural Sciences of the Environment
Research School for Socio-Economic and
Natural Sciences of the Environment

Pablo Rodríguez Sánchez

Date: 15 June 2020
Time: 13:30 - 15:00
Location: Auditorium, Wageningen University

Dissertation title: 

Cycles and interactions: a mathematician among biologists

Group: Aquatic Ecology and Water Quality Management, Wageningen University
Promotor: prof. dr M Scheffer
Co-promotor: dr ir EH van Nes


The backbone of this thesis is the interdisciplinary interaction between dynamic systems theory and a selection of biological problems. Each chapter focuses in one problem, namely plankton dynamics, cell development paths and sleep-wake dynamics. Despite these topics may seem disconnected, they share an important feature: all of them show cyclic behaviour under certain circumstances.
In the present thesis we show that cyclic (or chaotic) behaviour is deeply related with plankton biodiversity. We also use cycles to show, in an intuitive way, that Waddington’s epigenetic landscapes (a common visual tool in stem cell research) are poorly defined, and we provide a practical solution to this. Lastly, we provide an algorithm to forecast a transition between synchronized and non-synchronized cyclic systems (such as normal sleep – insomnia, or normal hearth functioning – arrhythmia), with potential applications in medical sciences.

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